Do you know that pesticides disrupt crucial biochemical pathways in our bodies, including the essential CYP450 system? This disruption triggers a cascade of health challenges.
Pesticides are classified as herbicides (targeting weeds), insecticides (targeting insects), fungicides (targeting fungal diseases), or other chemicals (targeting pests, materials, and crop foliage). Extensive research reveals their presence in our air, food, and water. Shockingly, in 2017, the United States dumped a staggering 1 billion pounds of conventional pesticides, as reported by the government agency, the United States Geological Survey.
According to the BioMed Journal, many of these pesticides, still used at high volumes in the US, have been banned or phased out in the EU, China, and Brazil. These banned pesticides have been linked to acute poisonings within the USA. Concerningly, the US EPA has largely relinquished non-voluntary cancellations, relying on industry consent for pesticide cancellation procedures.
The CYP450 enzymes, predominantly found in the liver, play a crucial role in metabolizing a wide range of harmful substances, including medications, toxins, and environmental pollutants. Pesticides disrupt the activity of specific CYP450 enzymes, such as CYP1A1 and CYP1A2, impairing their ability to effectively detoxify these harmful substances from our bodies.
IMPORTANT:
The disruption caused by pesticide exposure not only heightens our vulnerability to pesticide-related health problems but also impedes our body’s ability to metabolize other environmental toxins that enter our system. Consequently, this disruption significantly increases the toxic load on our liver, compromising its crucial functions such as detoxification, nutrient processing, and hormone regulation. Moreover, it adversely affects the integrity of other vital organs involved in maintaining overall health, such as the kidneys, lungs, and immune system. The repercussions of this disruption extend beyond individual organs, impacting interconnected physiological processes essential for optimal well-being.
The breakdown of CYP450 in our liver has profound implications for our health
- Compromised drug metabolism, leading to medication interactions and adverse effects.
- Impaired detoxification capabilities, resulting in an increased toxic burden.
- Disruption of metabolic pathways, contributing to conditions like obesity, diabetes, and dyslipidemia.
- Hormonal imbalances, including estrogen dominance and testosterone deficiency.
- Impaired detoxification of carcinogens, increasing the risk of cancer development.
- Impact on neurotransmitter production, contributing to neurological conditions such as depression, anxiety, and cognitive impairments.
- Heightened toxin levels, adversely affecting organ function and overall health.
The implications of CYP450 breakdown extend far beyond what has been mentioned here, emphasizing the profound impact of pesticide toxicity on our bodies, lives, and overall well-being.
Understanding how environmental toxins, chemicals, and poisons disrupt our body’s biochemical pathways and processes is paramount. It illuminates the consequences on our one “wild and precious life,” as poet, Mary Oliver penned. Focusing solely on dietary choices pales in comparison to this vital work. After all, how can any diet truly matter if our bodies are being shut down by chemicals?
This post underscores the urgency to address the detrimental effects of these toxins and prioritize strategies that mitigate their impact on our health, and I can help. Please email me here